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He Laboratory

About this business

The He Laboratory is primarily interested in understanding the molecular workings of Wnt/b-catenin signaling in normal development and human pathology. In the absence of a Wnt ligand, the Axin destruction complex phosphorylates b-catenin to be degraded, preventing b-catenin from reaching the nucleus. Canonical Wnt signaling is initiated by the binding of a Wnt protein to coreceptors Frizzled and Lrp5/6, which recruits the Axin destruction complex to the membrane and allows b-catenin to accumulate and enter the nucleus to alt... read more

Location details

Kirby Neurobiology Center, 3 Blackfan Circle F.M, Boston, MA, 02115, United States

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WeekdayScheduleStatus
Mon9:00 a.m. to 6:00 p.m.
Tue9:00 a.m. to 6:00 p.m.
Wed9:00 a.m. to 6:00 p.m.
Thu9:00 a.m. to 6:00 p.m.
Fri9:00 a.m. to 6:00 p.m.
SatClosed
SunClosed
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He Laboratory is open now. It will close at 6:00 p.m.  

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