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Best Hotels in Sikeston, MO

7 businesses found
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1Drury Hotels Company

4.6
1,416 reviews
2608 E Malone Ave, Sikeston, MO, 63801
  • Closed
  • Opens 9:00 a.m. Monday
HospitalityHotels

2Drury Inn & Suites Sikeston

4.6
1,359 reviews
2608 E Malone Ave, Sikeston, MO, 63801
  • Closed
  • Opens 9:00 a.m. Monday
HospitalityHotels

3Pear Tree Inn Sikeston

4.5
876 reviews
2602 E Malone Ave, Sikeston, MO 63801, Sikeston, MO, 63801
  • Closed
  • Opens 9:00 a.m. Monday
HospitalityHotels

4Hampton Inn Sikeston

4.3
637 reviews
1240 Commerce Drive, Sikeston, MO 63801, Sikeston, MO, 63801
  • Open
  • Closes 12:00 a.m. tomorrow
HospitalityHotels

5Country Hearth Inn & Suites - Sikeston

4.1
552 reviews
100 Matthews Ln, Sikeston, MO, 63801
  • Closed
  • Opens 9:00 a.m. Monday
HospitalityHotels

6Days Inn & Suites by Wyndham Sikeston

3.7
774 reviews
220 S Interstate Dr, Sikeston, MO 63801, Sikeston, MO, 63801
  • Open
  • Closes 12:00 a.m. tomorrow
HospitalityHotels

7Comfort Inn & Suites

4.0
654 reviews
109 Matthews Lane, Sikeston, MO, 63801
  • Closed
  • Opens 10:00 a.m. Monday
HospitalityHotels

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